Alpha chymotrypsine CHOAY

Alpha chymotrypsine CHOAY 

FORM AND PRESENTATION:

Tablet (white).

Blister of 10 tablets. Box of 2 blisters or box of 1 blister. COMPOSITION:

Each tablet contains:

Chymotrypsine or alphachymotrypsine          21(jkatals (or 25 C.Hb unity tablet)

Excipients q.s.: Peppermint oil, magnesium stearate, wheat starch, sugar.

INDICATION:

Enzymatic anti-oedema and anti-inflammatory:

Treatment of post - traumatic or postoperation oedema (i.e., soft tissue injuries, acute traumatic injuries, sprains, contusions, hematomas, ecchymoses, infections, edema of- the eyelids, muscle cramps, and sports injuries).

DOSAGE AND ADMINISTRATION:

Oral route:

2 tablets, 3 to 4 times/ day. Tablets should also be taken with at least 8 oz equivalent to 240 ml of water to help activate the enzyme.

Sublingual:

4 to 6 tablets/ day in divided doses. Tablet should be slowly dissolved under the tongue.

CONTRA-INDICATION:

Allergic to any components of the product.

chymotrypsine is contraindicated in patients with decreased alpha 1 antitrypsine. Generally, patients with COPD, especially emphysema and patients presenting with nephrotic syndrome are also likely candidates for decreased alpha 1 antitrypsine. UNDESIRABLE EFFECTS:

There do not appear to be any long-term side effects from chymotrypsin therapy if precautions for its use are followed in precaution in use.

Studies have shown that at recommended doses, enzymes cannot be detected in blood analysis after 24-48 hours. Temporary side effects that may occur (but that should disappear when therapy is discontinued or dosage is reduced) include changes in the color, consistency, and odor of the stool. Some individuals may experience gastrointestinal disturbances, such as flatulence, a feeling of fullness, diarrhea, constipation, or nausea.

With high doses, minor allergic reactions such as reddening of the skin may occur.

package insert, please inform your doctor.

PRECAUTION IN USE:

chymotrypsine is generally well tolerated and not associated with any significant side effects.

People who should not use enzyme therapy include those with hereditary clotting disorders such as hemophilia, those suffering from coagulation disturbances, those who are just about to or have undergone surgery, those on anticoagulant therapy, anyone suffering from protein allergies, and pregnant women or those breast-feeding, palient has stomach ulcers.

INTERACTIONS:

Chymotrypsine is most often used in combination with other enzymes to enhance its treatment potential. In addition,

a well-balanced diet or the 'OĨĨOÍ vitamin and mineral supplements are recommended to stimulate chymotrypsine activity.

Some types of seeds, including jojoba and wild soja seeds, have been found to contain proteins that inhibit the activity of chymotrypsine. These proteins can be inactivated by boiling the seeds.

Chymotrypsine should not be used together with acetylcysteine, a drug used to thin mucus in the lungs. It should also not be used together with anticoagulant (blood Jthinning) drugs, as it increases their effects.

PREGNANCY AND BREAST-FEEDING: chymotrypsine should not be used for pregnant and breast­feeding women.

PHARMACOKINETICS:

Chymotrypsine is a digestive enzyme that breaks down proteins (i.e., it is a proteolytic enzyme; it can also be referred to as a protease). It is naturally produced by the pancreas in the human body. However, it can also be taken as an enzyme supplement to improve health and digestion and aid in the treatment of various diseases.

Protease, which breaks protein molecules into dipeptides and some single amino acids. In addition to chymotrypsine, other protease enzymes secreted by the pancreas include trypsine and carboxypeptidase.

PHARMACODYNAMICS:

Enzymatic anti-oedema and anti-inflammatory.

As an anti-inflammatory agent, the chymotrypsine and the other protease enzymes prevent tissue damage during inflammation and the formation of fibrin clots. Protease enzymes participate in the breakdown of fibrin in a process called fibrinolysis. Fibrin causes a wall to form around an area of inflammation, resulting in the blockage of blood and lymph vessels, which leads to swelling. Fibrin can also cause the development of blood clots.

STORAGE:

Store in dry place, at temperature below 25°c.

SHELF LIFE: 18 months from the manufacturing date.

Prescription only medicine

Keep out of the reach of children

Read carefully the leaflet before use

If you have any questions, ask your doctor

Sanofi-syntheldbo

PHARMACEUTICAL SHAREHOLDING COMPANY SANOFI-SYNTHELABO VIETNAM 

(GMP-WHO certified)